National Institute of Communicable Diseases
Directorate General of Health Services
Ministry of Health and Family Welfare (GOI)
22, Sham Nath Marg, New Delhi-110 054

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NICD'S OBJECTIVES

Objectives and Functions

The objectives of the Institute broadly cover three activities viz., training, service and operational research in the field of communicable diseases and their prevention and control in the country.
 
The broad Objectives and Functions of the Institute are:

  • To advise Government on issues related to prevention and control of communicable diseases in the country.

  • To initiate enquiries and undertake investigations on communicable diseases including such problems as may be referred to the Institute by the Ministry of Health and Family Welfare, Government of India and the State Governments from time to time.

  • To assist the state health authorities in field investigations as may be undertaken by them and providing them with technical assistance wherever necessary.

  • To undertake operational research on prevalence and spread of communicable diseases and their prevention.

  • To carry-out epidemiological investigations, mapping-out of areas of endemicity, study of communicable disease statistics on modern lines and generally to elucidate the principles underlying the prevalence of communicable diseases in India.

  • To advise upon and assist in carrying-out control measures of communicable diseases and to study these scientifically and to evaluate them.

  • To undertake clinical investigations on communicable diseases and treatment. To study techniques of early diagnosis, relapse problems and to update and institute modern technologies and molecular methods for detection and surveillance of epidemic prone diseases.

  • To train research workers in the concerned disciplines.

  • To train personnel in epidemiology and control of communicable diseases.

  • To publish scientific results, technical guidelines, training manuals and bulletins.

  • Organise workshops on topics of topical interest like Epidemiology and Training, Rabies Epidemiology and Referral Laboratory for Poliomyelitis.

Operational Research

  • Undertake field studies on the taxonomy, biology, ecology, dynamics of disease transmission and control measures of vector borne diseases.

  • Develop newer tools, techniques, methodologies aimed at early detection/ improvement of diagnosis and epidemiological assessment of infections in the community.

  • Carry out in-depth operational research including development of modern molecular biology and biotechnology tools to define the epidemiological concepts viz., prevalence, endemicity level, spread and prevention of communicable diseases and to provide research support to the on going disease control programmes in the country.

  • Undertake laboratory and field evaluation of newer biocides/ insecticides/drugs and equipments used or intended to be used in vector/disease control practices. Specialised operational research is particularly undertaken in the field of bacteriology, virology, molecular biology, biotechnology, immunology, mycology, parasitology and helminthology with an aim to improve diagnostic capabilities of disease of public health importance and giving laboratory support to the investigation and control of disease outbreaks.The important diseases include Cholera, Polio Myelitis, Measles, Diphtheria, Meningitis, Tetanus, Hepatitis, AIDS, Rubella, Rabies, Dengue, Japanese Encephalitis, Kala-azar, Guinea Worm, Malaria, Filaria and some non-communicable diseases such as Iodine Deficiency Disorders, environmental pollution, Apo-B gene polymorphism in primary hyperlipidemia, disaster management and so on.

Other Supportive Services

  • The Institute provides support to the various National Health Programmes and Disease Surveillance activities through research expert advice and operational activities.

  • Advise the Government on various issues related to the communicable diseases in the country and their control.

  • Supply scientific and biological material to medical organisations for promotion of knowledge on communicable diseases and their control.

  • Supply biological control agents to State Governments, local bodies, defence services and other organisations for instituting biological control of mosquito vectors.

  • Undertake bio-efficacy tests of newer insecticides and their formulations from different industries/institutions to meet the requirement of Central Insecticide Board.

  • Undertake quality control of cold chain system by carrying out potency testing of field samples of oral polio vaccine and measles vaccine.

  • Undertake National External Quality Assurance Programmes in HIV & Rabies Testing and Others.

  • Diagnostic Support Services. The institute provides referral diagnostic services for various communicable diseases. Some of which are ordinarily not available in hospitals and medical colleges. These include diagnosis of poliomyelitis, Measles, Coxsackie virus, other enteroviruses. TORCH group of organisms, Viral Hepatitis, Meningitis, Diphtheria, Acute Respiratory infections. Cholera and newer enteropathogens, mycotic diseases, AIDS, Rabies, Kala-azar, Brucellosis, Rickettsioses, Leptospirosis, Hydatidosis, Arboviral infections, Plague, Anthrax etc.

  • Update and institute modern technologies and molecular methods for detection and surveillance of epidemic prone diseases.

  • Maintain reference laboratories on major diseases viz., Polio, AIDS, Rabies, Filaria, Guinea Worm, Yaws etc.

  • Act as a nodal point for testing and devising control of strategy formulated on a pilot scale before wider application.

  • Planning, guiding and evaluation of National Disease Surveillance Programme, Yaws Eradication Programme and support to Global Polio Eradication Programme.

  • Provide library facilities by way of supplying scientific bibliographies, reprints of research papers etc. to meet the needs of scientific workers to pursue research on communicable diseases in the country.

Library

The NICD Library came into being in 1909 along with the establishment of the Central Malaria Bureau at Kasauli (Himachal Pradesh) and since then the library facilities continued to expand with the increased activities and the renaming as Malaria Institute of India (MII). The expansion received a fillip in 1963, when the activities of Malaria Institute of India were expanded and reorganised and it was renamed as NICD.

NICD is the only library in the country which has got enormous early literature in the fields of malaria and other vector borne diseases prevalent in the country. The Library is having up to date literature on all the vector-borne diseases, communicable diseases and related aspects viz. Bacteriology, Parasitology, Microbiology, Infectious Diseases, Mycology, Biochemistry, Immunology etc. A total of 126 (Journal 85 foreign and 45 National) are subscribed. In addition about 100 journals are being received on exchange or on complimentary basis.

The library has a total of 29825 books and bound journals, 251 maps, 89 photocopies on various subjects and about 1276 annual reports from various organisations.

Some of the important indexing and abstracting journals available in the library are Tropical Diseases Bulletin, Abstracts of Hygiene, Excerpta Medica (Immunology and Microbiology), Index Medicus (Monthly) and Helminthology Abstracts.

The library maintains adequate stocks of reprints of a large number of papers and articles published in Indian Journal of Malariology and Journal of Communicable Diseases for supply to research workers in the country and abroad and participants to different courses at NICD. Similarly, the library also obtains reprints on research papers for research workers of the Institute.

Animal Facility

The Central Animal House provides laboratory to various divisions of NICD and also to other Government, Semi Govt. and Private Institutions. These animals are mainly used for diagnostic purpose for identification of the actiology of outbreks and for breeding colonies of various species of mosquitoes.

Animal Species used at NICD

The following animals are supplied by the Central Animal House to various Divisions of NICD for different experimental purposes:

S.No.  Animal  Species    Division  Project in which used
 1.  White mice  Zoonosis

 Rabies
 a) Mouse inoculation test
 b) Preparation of antigen used for rabies

 Toxoplasmosis
 a) Maintenance of Toxoplasma gondii strain for antigen preparation (used in
     serodiagnosis of Toxoplasmosis)

 Plague
 a) Isolation & purification of plague bacilli from field specimens.

 Entomology  Maintenance of rat flea (Xenopsylla cheopis) to study the residual effect of
  insectisides
 2.  White rat
 (Albino rat)
 Biochemistry

 Toxicology
 a) Pesticide feeding experiments
 b) Immunological studies related to pesticides effects

 Helminthology

 Filaria
  Maintenance of Litmosoides carinii Ornithomyssus bacoti mites.

 3.  Rabbits  Zoonosis

 Leishmania
 a) Blood is used for preparation of media used for maintaining the Leishmanis strains
 b) production of antisera used in sero-diagnosis of Leishmaniasis

  Toxoplasma
 a) production of antisera used in serodiagnosis of toxoplasmosis
  b) for detecting circulating antigen by gel diffusion test.

 Entomology  Feeding of mosquitoes (Anopheles stephensi and Aedes Aegyptii, sand flies and rat fleece)
 Biochemistry

 a) Study on pesticides
 b) Raising antisera for serodiagnosis

 4.  Guinea Pigs  Zoonosis  Serum for complement fixation test
 5.  Hamsters  Zoonosis  Maintenance of strain of Leishmania donovani
 5.  Hamsters  Zoonosis  Maintenance of strain of Leishmania donovani
 6.  Sheep  Microbiology  Media Preparation
 7.  Geese  Zoonosis  Virological studies
 8.  Fowls  Trg. and Malariology  Development of anti human and anti bovine sera for testing of blood meals of mosquitoes.
 9.  Monkeys  Microbiology  Measles
 Blood is used to test measles antibodies
 10.  Pigeon  Entomolgy  Feeding of mosquitoes (Culex quinquefasiatus)
 Helminthology  Filaria
 Feeding of mosquitoes (Aedes aegypti)
 11.  Fish
 (Larvivorous)
 Entomology  Gambusia affinis (Clean water) Poecilliaresticulatus(Dirty water) for Vector Control Studies.