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National Institute of Communicable Diseases |
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ANNUAL REPORT 1997 |
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NICD Branch,
Rajahmundry Regional
Filaria Training and Research Centre, Rajahmundry, under the division of
Helminthology, National Institute of Communicable Diseases was established in
1963. The main activities of the Centre are to carry out research on different
aspects of filariasis, impact training to various public health personnel and
service to public through clinic. Apart from the activities on filariasis, any
other duty assigned from time to time by the Director, viz. Investigations of
outbreak of communicable diseases, health surveys, etc., are also being carried
out by the Centre. Routine services / activities Service to public through weekly
filaria clinic
2477
blood smears received from 25NFCP Units of Andhra Pradesh were cross checked. As a
part of the training course in filariology for Health Inspectors/Technicians
during the month of December, a filaria survey was taken up at ELURU town of
West Godavari District. A total of 3398 blood smears were collected by random
sampling technique. The disease rate works out to 1.5%. The entomological
indices are as under:
Research Projects A study on the role of low density of carriers in the transmission of
filariasis In
filariasis endemic areas where the disease is under control, a few cases of low
density microfilaremia remain. The objective of this study is to determine
whether such cases play a role in the continuation of transmission. Veerabhadrapuram
village having a population of 506 situated in the endemic belt of East
Godavari district, (A.P.) was selected for the study. Baseline
clinico-epidemiological survey was carried out. The mf rate was 6.8% and
average mf density was 13.8. Mass chemotherapy with DEC 6 mg/kg body weight for
12 days was given to the population. After chemotherapy, the mf rate was
reduced to less than 0.5% and mf. density to 1 mf per 20 cmm of blood. Follow
up parasitiological surveys and routine entomological collections including
human bait collections were made at yearly interval. At one year, two year
interval follow up survey was done and the particulars are furnished in table
below: Clinic parasitological and
Entomological indices at Veerabhardrapuram village
Microfilaria
rate and average mf density in the human population were less in the follow up
surveys compared to base line data. Infection and infectivity rate in the
vector specieis was nil in the follow up study. Follow up study of W.bancrofti antigen positive endemic normals The
study was conducted to find out the prognostic significance of antigen test in
endemic normals and any correlation between antigen presence and
disease/carrier development at the later point of time. In May
1988, a filariasis survey was carried out in Kuthukuluru village of East
Godavari district A.P. A total of 484 blood smears were collected by finger
prick (20 cmm) method out of which, 125 were found positive and 359 negative
for mf. Blood samples of all these individuals i.e. 484 were subjected to
Immunological test at Helminthology division, NICD, Delhi by applying ELISA
technique using monoclonal antibodies. It was found that out of 359 whose blood
smears were negative for mf, 68 were found positive antigentically. Durring
the year 1996, 37 persons only could be contacted and blood smears were
collected.
The
results did not indicate any prognostic significance of the antigen test.
Hence, further study on this research project has ben discontinued. 1. Assessment of adequacy of
resources provided for filariasis control units under NFCP During
the National Seminar on “Operational research in Vector Control” at Calicut in
1990 and at the National Workshop to identify operational constraints their
feasible solution and resource needs for efficient functioning of NFCP Units,
it was felt that the available resources are not adequate to undertake
antifilarial activities as per guidelines given in the operational Manual on
Filariasis. The objectives of the study were: §
To
assess the adequacy of resources available in NFCP units to carryout
antifilarial activities and §
To
suggest minimum resources needs in Control units for efficient The
health functionaries of NFCP Units, Kakinada, Rajahmundry, Mandapeta, Ramachandrapuram
were interviewed on predesigned questionnaires. The data are under compilation.
2. Immunomonitoring of acute early
disease manifestation and occult filarial cases during DEC therapy This
project was initiated at RFT & RC, Calicuit in collaboration with Mahatma
Gandhi Institute of Medical Sciences, Wardha (Maharastra) and was to be
extended to RFT & RC, Rajahmundry for diagnosis and confirmation of
filarial aetiology in occult filarial infection such as TPE, monoarticular
arthritis, central serious retinopathy, acute abdomen etc. Prof. Harinath of
Wardha has expressed his inability to supply the antigen citing
non-availability and hence, the project could not be initiated. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
